Advancements and Current Trends in Next-Generation Sequencing (NGS) Technology
Abstract
NGS represents a ground-breaking technology facilitating swift, high-throughput sequencing of DNA or RNA molecules. NGS techniques empower the simultaneous parallel sequencing of millions to billions of DNA or RNA fragments, a capability unmatched by traditional Sanger sequencing, which is constrained by scalability and speed. The versatility of NGS platforms has expanded the scope of genomics research, enabling investigations into rare genetic diseases, cancer genomics, microbiome analysis, infectious diseases, and population genetics. Furthermore, NGS has paved the way for the advancement of targeted therapies, precision medicine strategies, and enhanced diagnostic methods.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
When publishing with Kerala Medicial Journal (KMJ), authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Work includes the material submitted for publication and any other related material submitted to KMJ. In the event that KMJ does not publish said work, the author(s) will be so notified and all rights assigned hereunder will revert to the author(s).
The assignment of rights to KMJ includes but is not expressly limited to rights to edit, publish, reproduce, distribute copies, include in indexes or search databases in print, electronic, or other media, whether or not in use at the time of execution of this agreement.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
The author(s) hereby represents and warrants that they are sole author(s) of the work, that all authors have participated in and agree with the content and conclusions of the work, that the work is original, and does not infringe upon any copyright, propriety, or personal right of any third party, and that no part of it nor any work based on substantially similar data has been submitted to another publication.
