Advancements and Current Trends in Next-Generation Sequencing (NGS) Technology

  • Hari Shankar DDRC Agilus Pathlabs Ltd, Kerala
  • R Krishnachandran DDRC Agilus Pathlabs Ltd, Kerala
  • MS Sinto DDRC Agilus Pathlabs Ltd, Kerala
Keywords: Genomics, Genes, Sequencing, Next-Generation

Abstract

NGS represents a ground-breaking technology facilitating swift, high-throughput sequencing of DNA or RNA molecules. NGS techniques empower the simultaneous parallel sequencing of millions to billions of DNA or RNA fragments, a capability unmatched by traditional Sanger sequencing, which is constrained by scalability and speed. The versatility of NGS platforms has expanded the scope of genomics research, enabling investigations into rare genetic diseases, cancer genomics, microbiome analysis, infectious diseases, and population genetics. Furthermore, NGS has paved the way for the advancement of targeted therapies, precision medicine strategies, and enhanced diagnostic methods.

Author Biographies

Hari Shankar, DDRC Agilus Pathlabs Ltd, Kerala

MBBS MD (Biochemistry)
Head, Department of Biochemistry & Immunology

R Krishnachandran, DDRC Agilus Pathlabs Ltd, Kerala

 Msc PhD, Head,
Department of Molecular Genetics & Cytogenetics, 

MS Sinto, DDRC Agilus Pathlabs Ltd, Kerala

MSc PhD, Department of Molecular Genetics & Cytogenetics

Published
2024-04-15
How to Cite
Shankar, H., Krishnachandran, R., & Sinto, M. (2024). Advancements and Current Trends in Next-Generation Sequencing (NGS) Technology. Kerala Medical Journal, 17(1), 32-34. https://doi.org/10.52314/kmj.2024.v17i1.627